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PROPERTY, PLANT AND EQUIPMENT
 12 Months Ended
Dec. 31, 2024
Property, Plant and Equipment [Abstract]  
PROPERTY, PLANT AND EQUIPMENT PROPERTY, PLANT AND EQUIPMENT
The following table summarizes our Property, plant and equipment, net by asset type:
December 31,
(in millions)20242023
Land and land improvements$561 $561 
Buildings and improvements (including leasehold improvements)4,539 4,328 
Laboratory and manufacturing equipment1,192 1,147 
Office, computer equipment and other1,090 1,069 
Construction in progress501 661 
Subtotal7,884 7,766 
Less: accumulated depreciation 2,470 2,449 
Total$5,414 $5,317 
The following table summarizes our Property, plant and equipment, net by geography:
December 31,
(in millions)20242023
U.S.$4,787 4,691 
International(1)
627 626 
Total$5,414 $5,317 
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(1)    All individual international locations accounted for less than 10% of the total balances.