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EMPLOYEE BENEFITS - Summary of Stock-Based Compensation (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses $ 796 $ 645 $ 635
Income tax effect (165) (91) (100)
Stock-based compensation expense, net of tax 630 553 535
Acquisition-related expense      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 29 8 0
Acquisition-related expense | XinThera, Inc      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 19    
Acquisition-related expense | Tmunity Therapeutics      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 10    
Acquisition-related expense | MiroBio Ltd.      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses   8  
Cost of goods sold      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 57 46 40
Research and development expenses      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 377 285 287
Selling, general and administrative expenses      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 361 313 308
RSUs      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 666 557 558
PSUs      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 32 25 17
Stock options      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses 30 28 29
ESPP      
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Stock-based compensation expense included in total costs and expenses $ 37 $ 26 $ 31