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Property, plant and equipment
12 Months Ended
Dec. 31, 2019
Property, Plant and Equipment Disclosure [Abstract]  
Property, Plant and Equipment
PROPERTY, PLANT AND EQUIPMENT
The following table summarizes our Property, plant and equipment (in millions):
 
 
December 31,
 
 
2019
 
2018
Land and land improvements
 
$
404

 
$
404

Buildings and improvements (including leasehold improvements)
 
3,358

 
2,344

Laboratory and manufacturing equipment
 
805

 
697

Office and computer equipment
 
634

 
558

Construction in progress
 
723

 
1,194

Subtotal
 
5,924

 
5,197

Less accumulated depreciation and amortization
 
(1,422
)
 
(1,191
)
Total
 
$
4,502

 
$
4,006


Office and computer equipment includes capitalized software. We had unamortized capitalized software costs on our Consolidated Balance Sheets of $108 million and $121 million as of December 31, 2019 and 2018, respectively. Capitalized interest on construction in-progress is included in property, plant and equipment. Interest capitalized in 2019, 2018 and 2017 was not material.