Employee Benefits - Summary of Stock-Based Compensation (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Document Fiscal Year Focus	2018
Share-based Compensation Expense	$ 845	$ 649	$ 380
Employee Service Share-based Compensation, Tax Benefit from Compensation Expense	(164)	(280)	(104)
Stock-based compensation expense, Net of Tax	681	369	276
Cost of Goods Sold
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Share-based Compensation Expense	61	24	14
Research and Development Expense [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Share-based Compensation Expense	379	232	176
Selling, General and Administrative Expenses [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Share-based Compensation Expense	$ 405	$ 393	$ 190