Property, plant and equipment

12 Months Ended

Dec. 31, 2018

Property, Plant and Equipment Disclosure [Abstract]

Property, Plant and Equipment

PROPERTY, PLANT AND EQUIPMENT

Property, plant and equipment is summarized as follows (in millions):

	December 31,
	2018			2017
Land and land improvements	$	404		$	396
Buildings and improvements (including leasehold improvements)	2,344			2,176
Laboratory and manufacturing equipment	697			533
Office and computer equipment	558			494
Construction in progress	1,194			690
Subtotal	5,197			4,289
Less accumulated depreciation and amortization	(1,191		)	(994		)
Total	$	4,006		$	3,295

Office and computer equipment includes capitalized software. We had unamortized capitalized software costs on our Consolidated Balance Sheets of $121 million and $129 million as of December 31, 2018 and 2017, respectively. Capitalized interest on construction in-progress is included in property, plant and equipment. Interest capitalized in 2018, 2017 and 2016 was not material.