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Organization and Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2017
Accounting Policies [Abstract]  
Property, Plant and Equipment, Estimated Useful Life
Estimated useful lives in years are generally as follows:
Description
Estimated Useful Life 
Buildings and improvements
20-35
Laboratory and manufacturing equipment
4-10
Office and computer equipment
3-7
Leasehold improvements
Shorter of useful life or lease term