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Property, plant and equipment
12 Months Ended
Dec. 31, 2017
Property, Plant and Equipment Disclosure [Abstract]  
Property, Plant and Equipment
PROPERTY, PLANT AND EQUIPMENT
Property, plant and equipment is summarized as follows (in millions):
 
 
December 31,
 
 
2017
 
2016
Land
 
$
396

 
$
394

Buildings and improvements (including leasehold improvements)
 
2,176

 
1,713

Laboratory and manufacturing equipment
 
533

 
469

Office and computer equipment
 
494

 
466

Construction in progress
 
690

 
641

Subtotal
 
4,289

 
3,683

Less accumulated depreciation and amortization
 
(994
)
 
(818
)
Total
 
$
3,295

 
$
2,865