May 5, 2020

Securities and Exchange Commission
Office of Filings and Information Services
100 F Street, NE
Washington, DC 20549

RE:BNY Mellon Investment Funds V, Inc.
- BNY Mellon Large Cap Equity Fund
- BNY Mellon Large Cap Growth Fund

1933 Act File No.: 33-44254
1940 Act File No.: 811-06490
CIK No.: 0000881773

Ladies and Gentlemen:

Pursuant to Rule 497(j) under the Securities Act of 1933, this is to certify that the form of the above-referenced Prospectuses and Statement of Additional Information that would have been filed under paragraph (b) or (c) of this section does not differ from that contained in the most recent amendment, Post-Effective Amendment No. 116 to the Registration Statement, electronically filed with the Securities and Exchange Commission on April 29, 2020.

Please address any comments or questions to my attention at 412-234-2521.

Sincerely,

/s/ Olivia M. Pollock
Olivia M. Pollock
Analyst/Paralegal