Consolidated Statements Of Cash Flow - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017
Cash flows from operating activities:
Net loss	$ (23,227)	$ (14,442)
Adjustments to reconcile net loss to net cash used for operating activities:
Depreciation and amortization	1,495	501
Amortization of debt issuance costs and discounts	10,706	9,973
Amortization of discount or premium on available-for-sale securities	616	442
Share-based compensation expense	1,974	1,468
Changes in assets and liabilities:
Accounts receivable	1,116	1,037
Inventories	(2,785)	558
Prepaid expenses and other assets	779	2,912
Accounts payable	(5,727)	(323)
Accrued and other liabilities	(2,469)	4,783
Deferred revenue	(609)	(18,197)
Net cash used for operating activities	(18,131)	(11,288)
Cash flows from investing activities:
Property and equipment purchases	(34)	(21)
Acquisition of PANCREAZE license	(135,000)
Purchases of available-for-sale securities	(7,604)	(20,915)
Proceeds from maturity of available-for-sale securities	40,411	23,120
Proceeds from sales of available-for-sale securities	60,259	7,208
Net cash provided by (used for) investing activities	(41,968)	9,392
Cash flows from financing activities:
Net proceeds from debt issuance	107,991
Repayments of notes payable	(57,187)	(6,507)
Net proceeds from exercise of common stock options	60
Sale of common stock through employee stock purchase plan	24	26
Net cash provided by (used for) financing activities	50,888	(6,481)
Net decrease in cash and cash equivalents	(9,211)	(8,377)
Cash and cash equivalents:
Beginning of period	66,392	84,783
End of period	$ 57,181	$ 76,406