Stock Option and Purchase Plans (Details 4) (USD $)	12 Months Ended				3 Months Ended	12 Months Ended
	Dec. 31, 2013 item	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2013 Proxy contest costs	Dec. 31, 2013 Employee severance costs	Dec. 31, 2013 Restricted stock units	Dec. 31, 2012 Restricted stock units	Dec. 31, 2013 Stock options	Dec. 31, 2012 Stock options	Dec. 31, 2011 Stock options	Dec. 31, 2013 Employee stock purchase plan	Dec. 31, 2012 Employee stock purchase plan	Dec. 31, 2011 Employee stock purchase plan	Dec. 31, 2013 Employee stock purchase plan Maximum	Dec. 31, 2013 Research and development	Dec. 31, 2012 Research and development	Dec. 31, 2011 Research and development	Dec. 31, 2013 Selling, general and administrative	Dec. 31, 2012 Selling, general and administrative	Dec. 31, 2011 Selling, general and administrative	Dec. 31, 2013 Non-recurring charges	Dec. 31, 2013 Inventory	Dec. 31, 2012 Inventory
Share-Based Compensation Expense
Share-based compensation expense before taxes	$ 32,397,000	$ 15,938,000	$ 7,353,000												$ 2,361,000	$ 3,487,000	$ 1,917,000	$ 15,964,000	$ 12,451,000	$ 5,436,000	$ 14,072,000
Share-based compensation expense, net of taxes	32,397,000	15,938,000	7,353,000			471,000	292,000	31,610,000	15,531,000	7,259,000	316,000	115,000	94,000
Number of employees reduced	20
Number of employees reduced (as a percent)	17.00%
Additional share-based compensation expense related to the automatic acceleration of vesting of unvested stock options held by the terminated employees					1,200,000
Total share-based compensation cost capitalized as part of cost of inventory				12,900,000																		480,000	196,000
Net share-based compensation expense, per common share:
Unrecognized estimated compensation expense								$ 12,200,000			$ 66,000
Weighted average remaining requisite service period								1 year 3 months 18 days						1 month
Weighted average assumptions for fair value of each option using the Black-Scholes option pricing model
Expected life								4 years 10 months 17 days	5 years 6 months 14 days	5 years 11 months 5 days
Volatility (as a percent)								83.35%	82.49%	77.46%
Risk-free interest rate (as a percent)								1.12%	1.00%	2.59%