Accrued and Other Liabilities (Details) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2013	Dec. 31, 2012
Accrued and Other Liabilities
Accrued employee compensation and benefits	$ 3,408	$ 3,859
Accrued manufacturing costs	4,071	4,135
Accrued sales and marketing expenses	970	2,908
Accrued interest on debt (see Note 12)	5,541
Accrued research and clinical expenses	1,755	1,372
Accrued restructuring costs (see Note 9)	4,577
Other accrued liabilities	3,671	1,503
Liabilities of discontinued operations		903
Total	$ 23,993	$ 14,680