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Accrued and Other Liabilities (Tables)
12 Months Ended
Dec. 31, 2013
Accrued and Other Liabilities  
Schedule of accrued and other liabilities

  Accrued and other liabilities consist of (in thousands):

 
  Balance as of  
 
  December 31,
2013
  December 31,
2012
 

Accrued employee compensation and benefits

  $ 3,408   $ 3,859  

Accrued manufacturing costs

    4,071     4,135  

Accrued sales and marketing expenses

    970     2,908  

Accrued interest on debt (see Note 12)

    5,541      

Accrued research and clinical expenses

    1,755     1,372  

Accrued restructuring costs (see Note 9)

    4,577      

Other accrued liabilities

    3,671     1,503  

Liabilities of discontinued operations

        903  
           

Total

  $ 23,993   $ 14,680