Income Taxes (Tables)

12 Months Ended

Dec. 31, 2012

Income Taxes

Schedule of significant components of deferred income tax assets

	2012			2011
Deferred tax assets:
Net operating loss carry forwards	$	154,865		$	107,241
Research and development credit carry forwards		13,192			14,468
Stock based compensation		9,386			—
Accruals and other		5,528			13,197
Depreciation		185			790
Deferred revenue		420			—
		183,576			135,696
Valuation allowance		(183,576	)		(135,696	)
Total	$	—		$	—

Schedule of (loss)/income from continuing operations before (benefit)/provision for income taxes

The (benefit)/provision for income taxes is based upon (loss)/income from continuing operations before (benefit)/provision for income taxes as follows, for the years ended December 31, 2012, 2011 and 2010 (in thousands):

	2012			2011			2010
Loss before income taxes:
Domestic	$	(138,599	)	$	(46,836	)	$	(75,425	)
International		(1,107	)		—			—
Loss before taxes	$	(139,706	)	$	(46,836	)	$	(75,425	)

Income Tax Disclosures

Schedule of reconciliation between the U.S. federal statutory tax rate and effective tax rate from continuing operations

	2012			2011			2010
Tax at U.S. federal statutory rate		(35	)%		(35	)%		(35	)%
Change in valuation allowance		34			38			35
Permanent items		1			1			1
Extinguishment of debt		—			—			3
Tax credits		—			(4	)		(4	)
Effective tax rate		0	%		0	%		0	%

Schedule of reconciliation of unrecognized tax benefits

	2012		2011		2010
Unrecognized tax benefits as of January 1	$	1,215	$	1,171	$	—
Gross increase/(decrease) for tax positions of prior years		—		44		1,171
Gross increase/(decrease) for tax positions of current year		—		—		—
Settlements		—		—		—
Lapse of statute of limitations		—		—		—
Unrecognized tax benefits balance at December 31	$	1,215	$	1,215	$	1,171

Schedule of unrecognized tax benefits recorded on consolidated balance sheets

 The total unrecognized tax benefits as of December 31, 2012 of $1.2 million includes approximately $1.1 million of unrecognized tax benefits that have been netted against the related deferred tax assets. The remaining balance recorded on the Company's consolidated balance sheets as of December 31, 2012 and 2011 is as follows (in thousands):

	2012			2011
Total unrecognized tax benefits	$	1,215		$	1,215
Amounts netted against deferred tax assets		(1,055	)		(1,055	)
Unrecognized tax benefits recorded on consolidated balance sheets	$	160		$	160

Continuing operations

Income Tax Disclosures

Schedule of components of (benefit)/provision for income taxes

The (benefit)/provision for income taxes consists of the following components for the years ended December 31, 2012, 2011 and 2010 (in thousands):

• Continuing Operations:

	2012		2011		2010
Current
Federal	$	—	$	—	$	—
State		27		190		9
Foreign		—		—		—
Total current (benefit)/provision for income taxes	$	27	$	190	$	9
Deferred
Federal	$	—	$	—	$	—
State		—		—		—
Foreign		—		—		—
Total deferred benefit for income taxes	$	—	$	—	$	—
Total (benefit)/provision for income taxes from continuing operations	$	27	$	190	$	9

Discontinued operations

Income Tax Disclosures

Schedule of components of (benefit)/provision for income taxes

The (benefit)/provision for income taxes consists of the following components for the years ended December 31, 2012, 2011 and 2010 (in thousands):

• Discontinued Operations:

	2012		2011		2010
Total (benefit)/provision for income taxes from discontinued operations	$	—	$	—	$	29