X0303 4 2011-03-01 0 0000881464 AMYLIN PHARMACEUTICALS INC AMLN 0001222356 MARCHETTI ROGER 9360 TOWNE CENTRE DR SAN DIEGO CA 92121 0 1 0 0 SVP, Human Resources & IM Common Stock 2011-03-01 4 A 0 15000 0 A 22284.2 D Common Stock 2011-03-01 4 A 0 1630.1 0 A 6445.1 I by ESOP Common Stock 1998.7 I Indirect-401k Incentive Stock Option (right to buy) 15.03 2011-03-01 4 A 0 8032 0 A 2018-03-01 Common Stock 8032 8032 D Non-Qualified Stock Option (right to buy) 15.03 2011-03-01 4 A 0 61968 0 A 2018-03-01 Common Stock 61968 61968 D Represents a restricted stock unit award that vests in three equal annual installments from the date of grant. Restricted stock units are generally settled in shares of common stock of the company on the vesting date. Includes 2,357 shares recently acquired under the Company's Employee Stock Purchase Plan. These shares fully vested four years from the date of the reporting person's participation in the ESOP in four equal annual installments and are generally distributed upon termination of employment. 25% of shares vest one year from the date of grant and the remainder vest in three equal annual installments becoming fully vested four years from the date of grant. By: /s/ James R. Oehler, Attorney-in-Fact For: Roger Marchetti 2011-03-03