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Collaborative Agreements (Narrative) (Details) (USD $)
3 Months Ended 3 Months Ended 3 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Dec. 31, 2011
Mar. 31, 2012
Takeda Agreement [Member]
Mar. 31, 2012
Alkermes Agreement [Member]
Mar. 31, 2012
The Lilly Agreement [Member]
Mar. 31, 2012
The Lilly Agreement [Member]
European Union Launch Of BYDUREON [Member]
Mar. 31, 2012
Takeda Agreement [Member]
Y
Oct. 31, 2009
Takeda Agreement [Member]
Collaborative Agreements [Line Items]                  
Milestone Payment         $ 7,000,000        
Percentage of shared Exenatide global development and commercialization expenses (US and outside US)           47.00% 53.00%    
Collaborative profit-sharing 0 59,851,000              
Lilly percentage of Exenatide global development and commercialization expenses (foreign)           100.00%      
Upfront payment received                 75,000,000
Estimated development period, years               10  
Deferred collaborative revenue       56,900,000          
Deferred revenue, net of current portion $ 49,375,000   $ 51,250,000 $ 49,400,000