Consolidated Balance Sheets (USD $) In Thousands, unless otherwise specified	Mar. 31, 2012	Dec. 31, 2011
Current assets:
Cash and cash equivalents	$ 73,401	$ 99,859
Short-term investments	231,225	104,206
Restricted cash	10,673	10,519
Accounts receivable, net	52,832	45,489
Inventories, net	135,507	111,959
Other current assets	57,611	49,158
Total current assets	561,249	421,190
Property, plant and equipment, net	829,707	831,162
Intangible asset related to reacquired economic interest, net	266,061	273,842
Economic interest in exenatide products to be reacquired as a business	327,697	327,697
Other long-term assets	22,557	16,308
Total assets	2,007,271	1,870,199
Current liabilities:
Accounts payable	33,673	21,035
Accrued compensation	36,305	66,776
Payable to collaborative partner	3,568	29,140
Restructuring liability, current portion	5,226	8,405
Promissory note related to revenue sharing obligation, current portion	68,304	63,552
Deferred revenue, current portion	7,500	7,500
Loss protection liability	37,283	0
Other current liabilities	98,347	99,609
Total current liabilities	290,206	296,017
Deferred revenue, net of current portion	49,375	51,250
Restructuring liability, net of current portion	23,079	23,877
Convertible senior notes	503,274	496,037
Note payable, net of discount	155,602	155,064
Promissory note related to revenue sharing obligation, net of current portion	947,092	924,306
Other long-term obligations, net of current portion	30,352	62,393
Commitments and contingencies	0	0
Stockholders' deficit:
Preferred stock, $.001 par value, 7,500 shares authorized, none issued and outstanding at March 31, 2012 and December 31, 2011	0	0
Common stock, $.001 par value, 450,000 shares authorized, 162,579 and 146,289 issued and outstanding at March 31, 2012 and December 31, 2011, respectively	162	146
Additional paid-in capital	2,750,744	2,506,013
Accumulated deficit	(2,742,619)	(2,643,579)
Accumulated other comprehensive loss	4	(1,325)
Total stockholders' equity (deficit)	8,291	(138,745)
Total liabilities and stockholders' equity	$ 2,007,271	$ 1,870,199