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Note 12 - Summary of Stock Options (Details Textual) - USD ($) $ / shares in Units, Pure in Thousands		1 Months Ended	3 Months Ended			6 Months Ended		12 Months Ended
	Jan. 01, 2022	Jan. 31, 2021	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021	May 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance (in shares)			4,124,009			4,124,009		3,173,103
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share)			$ 6.06			$ 6.06		$ 7.51
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term (Year)						8 years 9 months 18 days		9 years
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares)						955,000
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate			0.00%		0.00%	0.00%	0.00%
Share-Based Payment Arrangement, Expense			$ 909,000		$ 867,000	$ 1,869,000	$ 1,677,000
Employees and Nonemployees [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares)			14,000		2,213,600	955,000	2,200,600
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value (in dollars per share)			$ 0.53		$ 1.87	$ 0.92	$ 1.87
Restricted Stock Units (RSUs) [Member]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total			$ 603,000			$ 603,000
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year)						7 months 6 days
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period (Year)						2 years
Share-Based Payment Arrangement, Expense			274,000		$ 276,000	$ 548,000	$ 500,000
Share-Based Payment Arrangement, Option [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate						0.00%
Dividend, Share-Based Payment Arrangement, Total						$ 0
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total			$ 5,401,000			$ 5,401,000
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year)						2 years 7 months 6 days
The 2006 Stock Option Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance (in shares)			12			12
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant (in shares)			0			0
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share)			$ 9,920.00			$ 9,920.00
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term (Year)						7 months 6 days
The 2013 Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance (in shares)			4,123,997			4,123,997
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant (in shares)			220,319			220,319
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share)			$ 6.03			$ 6.03
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term (Year)						8 years 9 months 18 days
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized (in shares)	1,076,833
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares)	5,016,969							3,940,136
The 2013 Plan [Member] \| Restricted Stock Units (RSUs) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number, Ending Balance (in shares)			674,000			674,000
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)						0
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period (in shares)					3,000	0	6,000
The 2013 Plan [Member] \| Restricted Stock Units (RSUs) [Member] \| Employees and Board Members [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)		690,000
The 2013 Plan [Member] \| Restricted Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number, Ending Balance (in shares)			228			228
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)						0
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period (in shares)					0	0	2
2017 Employee Stock Purchase Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant (in shares)			426,674			426,674
Common Stock, Capital Shares Reserved for Future Issuance (in shares)					500,378		500,378		400
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant During Offering Period (in shares)					2,000		2,000		2
Stock Issued During Period, Shares, Employee Stock Purchase Plans (in shares)			24,505	20,691
Shares Issued, Price Per Share (in dollars per share)			$ 0.56	$ 0.90		$ 0.56
Share-Based Payment Arrangement, Expense			$ 8,000			$ 15,000