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Note 14 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2021
Notes Tables  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
  

Year Ended

December 31,

 
  

2021

  

2020

 
         

Income tax benefit at statutory rate

  (21)%  (21)%

State income taxes, net of federal benefit

  (3)%  (3)%

Change in valuation allowance

  21%  20%

Other

  3%  4%

Effective tax rate

  0%  0%
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
  

Year Ended

December 31,

 
  

2021

  

2020

 

Deferred tax assets:

        

Net operating loss carryforwards

 $25,092  $20,891 

Capitalized start up costs

  2,511   2,866 

Research and development credits

  781   631 

Accruals and reserves

  1,537   773 

Fixed assets and depreciation

  124   291 

Total deferred tax assets

  30,045   25,452 

Deferred tax liabilities:

        

Valuation allowance

  (30,045)  (25,452)
         

Net deferred tax assets

 $-  $- 
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
  

Year Ended

December 31,

 
  

2021

  

2020

 
         

Balance at the beginning of the year

 $245  $223 

Additions (deletions) based upon tax positions related to the current year

  (14)  22 

Balance at the end of the year

 $231  $245