Note 12 - Summary of Stock Options - Valuation Assumption for Employee Stock Purchase Plan (Details)	3 Months Ended	9 Months Ended
Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Expected term (Year)	5 years		5 years	5 years
Average volatility	87.00%		81.00%	73.00%
Risk-free interest rate	0.27%		0.34%	2.49%
Dividend yield
2017 Employee Stock Purchase Plan [Member]
Expected term (Year)	91 days	91 days	91 days	91 days
Average volatility	76.00%	98.00%	106.00%	84.00%
Risk-free interest rate	0.14%	2.21%	0.66%	2.40%
Dividend yield	0.00%	0.00%	0.00%	0.00%

The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term.

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- Definition

The risk-free interest rate assumption that is used in valuing an option on its own shares.

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- Definition

Rate of weighted-average expected volatility for award under share-based payment arrangement.

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- Definition

Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
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-URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809

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