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Note 8 - Summary of Stock Options - Summary of Option Activity Under All Plans (Details)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2016
USD ($)
$ / shares
shares
Dec. 31, 2015
$ / shares
shares
Options outstanding, beginning of period (in shares) | shares 1,022,195  
Options outstanding, beginning of period (in dollars per share) | $ / shares $ 6.47  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term 8 years 339 days 9 years 135 days
Options granted (in shares) | shares 378,932  
Options granted (in dollars per share) | $ / shares $ 7.25  
Options exercised (in shares) | shares (3,020)  
Options exercised (in dollars per share) | $ / shares $ 4.80  
Options canceled (in shares) | shares (82,299)  
Options canceled (in dollars per share) | $ / shares $ 7.55  
Options outstanding, end of period (in shares) | shares 1,315,808 1,022,195
Options outstanding, end of period (in dollars per share) | $ / shares $ 6.63 $ 6.47
Options outstanding, end of period | $ $ 1,615,644  
Vested and exercisable and expected to vest, end of period, Number Of Shares (in shares) | shares 1,221,813  
Vested and exercisable and expected to vest, end of period, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 6.65  
Vested and exercisable and expected to vest, end of period, Weighted Average Remaining Contractual Term 8 years 328 days  
Vested and exercisable and expected to vest, end of period, Aggregate Intrinsic Value | $ $ 1,523,776  
Vested and exercisable, end of period, Number Of Shares (in shares) | shares 279,725  
Vested and exercisable, end of period, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 8.05  
Vested and exercisable, end of period, Weighted Average Remaining Contractual Term 7 years 306 days  
Vested and exercisable, end of period, Aggregate Intrinsic Value | $ $ 473,807