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Note 2 - Summary of Significant Accounting Policies (Tables)
3 Months Ended 12 Months Ended
Mar. 31, 2016
Dec. 31, 2015
Notes Tables    
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
 
 
Three Months Ended
 
 
 
March 31,
 
 
 
2016
 
 
2015
 
                 
Stock options to purchase common stock
    1,131,768       363,252  
Warrants to purchase common stock
    401,446       301,399  
Rights to common stock
    -       70,755  
 
 
Year Ended
December 31,
 
 
 
2015
 
 
2014
 
                 
Stock options to purchase common stock
    1,022,195       286,501  
Warrants to purchase common stock
    383,321       224,248  
Rights to common stock
    -       70,755