Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (175,218)	$ (135,376)
Adjustments to reconcile net loss to net cash flow from operating activities
Stock-based compensation	15,209	19,694
Depreciation and amortization	5,235	4,263
Accretion of note premiums/discounts	(5,704)	(835)
Realized loss on investments	0	(80)
Non-cash interest expense on liability related to the sale of future royalties	5,415	5,367
Non-cash interest expense on credit facility	16,231	0
Changes in operating assets and liabilities:
Accounts receivable	(2,500)	0
Prepaid expenses and other assets	(592)	(1,748)
Accounts payable	3,069	(12,463)
Accrued expenses	(7,691)	408
Deferred revenue	0	(866)
Operating lease, net	(1,128)	3,796
Other	1,402	0
Net cash used in operating activities	(146,272)	(117,840)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property and equipment	(7,516)	(68,656)
Purchases of investments	(33,749)	0
Proceeds from sales and maturities of investments	118,175	133,495
Net cash provided by investing activities	76,910	64,839
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from the exercises of stock options	634	267
Proceeds from the issuance of pre-funded warrants	25,000	0
Payments of debt issuance cost	(5,000)	0
Net cash provided by financing activities	20,634	267
Net decrease in cash, cash equivalents and restricted cash	(48,728)	(52,734)
Effect of exchange rate on cash, cash equivalents and restricted cash	(68)	58
CASH, CASH EQUIVALENTS AND RESTRICTED CASH:
BEGINNING OF PERIOD	102,685	110,891
END OF PERIOD	53,889	58,215
Supplementary disclosure of cash flows:
Income taxes paid	(11)	(999)
Supplemental disclosure of non-cash investing activities:
Capital expenditures included in accrued expenses	$ 2,574	$ 11,290