Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
CASH FLOWS FROM OPERATING ACTIVITIES:
Net (loss) income	$ (262,372)	$ 5,865
Adjustments to reconcile net loss to net cash flow from operating activities
Stock-based compensation	37,444	40,002
Depreciation and amortization	8,788	5,358
Amortization (accretion) of note premiums/discounts	896	(82)
Realized gain on investments	(80)	0
Non-cash interest expense on liability related to the sale of future royalties	12,612	7,906
Changes in operating assets and liabilities:
Accounts receivable	0	(68,024)
Prepaid expenses and other current assets	(2,643)	20,309
Accounts payable	(8,402)	6,688
Accrued expenses	(11)	(27,279)
Deferred revenue	(866)	(99,135)
Operating lease, net	4,417	1,205
Net cash used in operating activities	(210,217)	(107,187)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property and equipment	(102,731)	(66,225)
Purchases of investments	(309,982)	(192,528)
Proceeds from sales and maturities of investments	208,615	141,994
Net cash used in investing activities	(204,098)	(116,759)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from the exercises of stock options	1,779	1,096
Proceeds from the issuance of common stock, net of offering costs	429,265	0
Proceeds from the sale of future royalties	0	250,000
Net cash provided by financing activities	431,044	251,096
Net increase in cash, cash equivalents and restricted cash	16,729	27,150
Effect of exchange rate on cash, cash equivalents and restricted cash	84	(196)
CASH, CASH EQUIVALENTS AND RESTRICTED CASH:
BEGINNING OF PERIOD	110,891	108,005
END OF PERIOD	127,704	134,959
Supplementary disclosure of cash flows:
Income taxes paid	(3,014)	0
Supplemental disclosure of noncash investing activities:
Capital expenditures included in accrued expenses	$ 7,265	$ 12,831