Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (135,376)	$ (41,811)
Adjustments to reconcile net loss to net cash flow from operating activities
Stock-based compensation	19,694	19,390
Depreciation and amortization	4,263	2,689
(Accretion) amortization of note premiums/discounts	(835)	690
Realized gain on investments	(80)	0
Non-cash interest expense on liability related to the sale of future royalties	5,367	2,849
Changes in operating assets and liabilities:
Accounts receivable	0	(38,157)
Prepaid expenses and other current assets	(1,748)	10,529
Accounts payable	(12,463)	(2,072)
Accrued expenses	408	(7,203)
Deferred revenue	(866)	(22,979)
Operating lease, net	3,796	559
Net cash used in operating activities	(117,840)	(75,516)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property and equipment	(68,656)	(38,911)
Purchases of investments	0	(111,199)
Proceeds from sales and maturities of investments	133,495	69,416
Net cash provided by (used in) investing activities	64,839	(80,694)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from the exercises of stock options	267	576
Proceeds from the sale of future royalties	0	250,000
Net cash provided by financing activities	267	250,576
Net (decrease) increase in cash, cash equivalents and restricted cash	(52,734)	94,366
Effect of exchange rate on cash, cash equivalents and restricted cash	58	(122)
CASH, CASH EQUIVALENTS AND RESTRICTED CASH:
BEGINNING OF PERIOD	110,891	108,005
END OF PERIOD	58,215	202,249
Supplementary disclosure of cash flows:
Interest paid	0	0
Income taxes (paid) refunded	(999)	0
Supplemental disclosure of noncash investing activities:
Capital expenditures included in accrued expenses	$ 11,290	$ 14,044