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Insider Trading Arrangements
 3 Months Ended 12 Months Ended
Sep. 30, 2023
shares
Sep. 30, 2023
shares
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement  
During the quarter ended September 30, 2023, the following directors and officers (as defined in Exchange Act Rule 16a-1(f)) adopted certain trading plans intended to satisfy Rule 10b5-1(c):
NameTitle
Adoption or Termination Date
Plan Start DatePlan End Date
Shares Vesting and Subject to Sell-To-Cover (1)
Other Shares Being Sold (Subject to Certain Conditions)
Mauro FerrariBoard Member09/28/202301/11/202401/31/2024n/a3,147
Douglass GivenBoard Member09/26/202301/11/202401/31/2024n/a2,911
James Hamilton (2)
Chief Discovery and Translational Medicine08/15/202301/03/202401/31/202452,500n/a
James HamiltonChief Discovery and Translational Medicine08/22/202312/01/202311/29/2024n/a35,000
Ken MyszkowskiChief Financial Officer09/07/202301/05/202401/31/202430,000n/a
Patrick O’Brien
Chief Operating Officer and General Counsel09/03/202301/03/202401/05/2024n/a4,000
Tracie OliverChief Commercial Officer08/28/202301/05/202407/31/202417,625n/a
Victoria VakienerBoard Member09/28/202301/11/202405/31/2024n/a6,519
William WaddillBoard Member08/29/202301/11/202401/31/2024n/a3,934
(1) This column indicates the total number of shares vesting, but the 10b5-1 Plan provides for the sale of only those shares necessary to satisfy payment of applicable withholding taxes.
(2) Termination of a trading plan that was intended to satisfy Rule 10b5-1(c).
Non-Rule 10b5-1 Arrangement Adopted   false
Non-Rule 10b5-1 Arrangement Terminated   false
Mauro Ferrari [Member]    
Trading Arrangements, by Individual    
Name Mauro Ferrari  
Title Board Member  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 09/28/2023  
Arrangement Duration   20 days
Aggregate Available 3,147 3,147
Douglass Given [Member]    
Trading Arrangements, by Individual    
Name Douglass Given  
Title Board Member  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 09/26/2023  
Arrangement Duration   20 days
Aggregate Available 2,911 2,911
Ken Myszkowski [Member]    
Trading Arrangements, by Individual    
Name Ken Myszkowski  
Title Chief Financial Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 09/07/2023  
Arrangement Duration   26 days
Aggregate Available 30,000 30,000
Patrick O'Brien [Member]    
Trading Arrangements, by Individual    
Name Patrick O’Brien  
Title Chief Operating Officer and General Counsel  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 09/03/2023  
Arrangement Duration   2 days
Aggregate Available 4,000 4,000
Tracie Oliver [Member]    
Trading Arrangements, by Individual    
Name Tracie Oliver  
Title Chief Commercial Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 08/28/2023  
Arrangement Duration   208 days
Aggregate Available 17,625 17,625
Victoria Vakiener [Member]    
Trading Arrangements, by Individual    
Name Victoria Vakiener  
Title Board Member  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 09/28/2023  
Arrangement Duration   141 days
Aggregate Available 6,519 6,519
William Waddill [Member]    
Trading Arrangements, by Individual    
Name William Waddill  
Title Board Member  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 08/29/2023  
Arrangement Duration   20 days
Aggregate Available 3,934 3,934
James Hamilton Terminated Plan [Member] | James Hamilton [Member]    
Trading Arrangements, by Individual    
Name James Hamilton  
Title Chief Discovery and Translational Medicine  
Rule 10b5-1 Arrangement Terminated true  
Termination Date 08/15/2023  
Arrangement Duration   28 days
Aggregate Available 52,500 52,500
James Hamilton August 2023 Plan [Member] | James Hamilton [Member]    
Trading Arrangements, by Individual    
Name James Hamilton  
Title Chief Discovery and Translational Medicine  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 08/22/2023  
Arrangement Duration   364 days
Aggregate Available 35,000 35,000