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Organization and Significant Accounting Policies - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Nov. 09, 2022
Jun. 30, 2023
Mar. 31, 2023
Jun. 30, 2023
Sep. 30, 2022
Organization And Significant Accounting Policies [Line Items]          
Cash, cash equivalents and restricted cash   $ 105,300   $ 105,300  
Restricted cash   7,300   7,300  
Short term investments   346,369   346,369 $ 268,391
Long-term investments   42,758   42,758 $ 105,872
Increase in cash and investments       12,200  
Development regulatory and sales milestones payments   3,400,000   3,400,000  
Horizon and Amgen          
Organization And Significant Accounting Policies [Line Items]          
Upfront milestone payment received       110,000  
Takeda | License and Co-Funding Agreement          
Organization And Significant Accounting Policies [Line Items]          
Milestone payment receivable   40,000   40,000  
GSK | Collaboration and License agreements          
Organization And Significant Accounting Policies [Line Items]          
Milestone payment receivable   30,000   30,000  
Horizon          
Organization And Significant Accounting Policies [Line Items]          
Upfront milestone payment received   $ 15,000 $ 15,000    
Amgen          
Organization And Significant Accounting Policies [Line Items]          
Upfront milestone payment received     $ 25,000    
Royalty Pharma          
Organization And Significant Accounting Policies [Line Items]          
Upfront milestone payment received $ 250,000     $ 250,000