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Collaboration and License Agreements - Amgen, Inc (Details)
$ in Thousands
Sep. 28, 2016
USD ($)
agreement
Mar. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Sep. 30, 2022
USD ($)
Jul. 31, 2020
USD ($)
Sep. 30, 2018
USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Contract liabilities   $ 29,839   $ 74,099    
Amgen | Collaboration and License agreements            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Number of agreements | agreement 2          
Amgen | Olpasiran and ARO-AMG1 Agreement            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Upfront payment $ 35,000          
Proceeds from the issuance of common stock $ 21,500          
Milestone payments   55,000 $ 25,000   $ 20,000 $ 10,000
Contract assets   0        
Contract liabilities   0        
Amgen | Olpasiran Agreement | Maximum            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Additional remaining development regulatory and sales milestones payments   $ 535,000