Collaboration and License Agreements - Horizon Therapeutics Ireland DAC (Details)		3 Months Ended
	Jun. 18, 2021 USD ($) bundle obligation	Mar. 31, 2023 USD ($)	Jan. 31, 2023 USD ($)	Sep. 30, 2022 USD ($)	Jul. 31, 2021 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Development regulatory and sales milestones payments		$ 3,600,000,000
Contract liabilities		29,839,000		$ 74,099,000
Horizon
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Upfront milestone payment received		15,000,000
Horizon | ARO-XDH
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Cash received as due under collaboration agreement					$ 40,000,000
Milestone payment			$ 15,000,000
Number of distinct performance obligations | obligation	1
Initial transaction price	$ 40,000,000
Contract assets		0
Contract liabilities		$ 0
Horizon | License Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of distinct bundle | bundle	1
Number of distinct performance obligations | obligation	1
Horizon | Maximum | ARO-XDH
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Development regulatory and sales milestones payments	$ 645,000,000