Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (41,811)	$ (62,872)
Adjustments to reconcile net loss to net cash flow from operating activities
Stock-based compensation	19,390	24,504
Depreciation and amortization	2,689	2,573
Amortization (accretion) of note premiums/discounts	690	(280)
Non-cash interest expense on liability related to the sale of future royalties	2,849	0
Changes in operating assets and liabilities:
Accounts receivable	(38,157)	10,105
Prepaid expenses and other current assets	10,529	(450)
Accounts payable	(2,072)	(5,389)
Accrued expenses	(7,203)	(2,290)
Deferred revenue	(22,979)	(27,439)
Operating lease liabilities	559	230
Net cash used in operating activities	(75,516)	(61,308)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property and equipment	(38,911)	(5,778)
Purchases of investments	(111,199)	(65,875)
Proceeds from sales and maturities of investments	69,416	38,268
Net cash used in investing activities	(80,694)	(33,385)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from the exercises of stock options	576	1,885
Proceeds from the sale of future royalties	250,000	0
Net cash provided by financing activities	250,576	1,885
Net increase (decrease) in cash, cash equivalents and restricted cash	94,366	(92,808)
Effect of exchange rate on cash, cash equivalents and restricted cash	(122)	(39)
CASH, CASH EQUIVALENTS AND RESTRICTED CASH:
BEGINNING OF PERIOD	108,005	184,434
END OF PERIOD	202,249	91,587
Supplementary disclosures:
Interest paid	0	0
Income taxes (paid) refunded	$ 0	$ 0