Organization and Significant Accounting Policies - Additional Information (Detail) $ in Thousands		3 Months Ended
	Dec. 20, 2021 ft² a	Dec. 31, 2021 USD ($)	Nov. 19, 2021 ft²	Sep. 30, 2021 USD ($)
Organization And Significant Accounting Policies [Line Items]
Cash and cash equivalents		$ 91,587		$ 184,434
Restricted Cash		3,000
Short-term investments		112,537		56,627
Marketable securities		126,000
Long-term investments		217,572		$ 245,595
Net increase (decrease) in cash and investments		65,700
Janssen
Organization And Significant Accounting Policies [Line Items]
Development regulatory and sales milestones payments		$ 6,200,000
Drug Manufacturing Facility | Wisconsin
Organization And Significant Accounting Policies [Line Items]
Planned area of the site | ft²	140,000
Research Facility In San Diego | California
Organization And Significant Accounting Policies [Line Items]
Office space leases, in square feet | ft²			144,000
Verona Technology Park | Wisconsin
Organization And Significant Accounting Policies [Line Items]
Land purchased, number of acres | a	13