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Subsequent Events - Additional Information (Detail)
Oct. 23, 2020
USD ($)
ft²
Oct. 07, 2020
USD ($)
Sep. 30, 2019
USD ($)
Subsequent Event [Line Items]      
Estimated lease payments     $ 22,385,552
Subsequent Event | Corporate Headquarters In Pasadena | California      
Subsequent Event [Line Items]      
Office space leases, in square feet | ft² 24,434    
Lease commencement period 2021-07    
Lease expiration month and year 2027-04    
Estimated lease payments $ 7,300,000    
Expected leasehold improvements, net of tenant improvement allowances $ 4,000,000.0    
Takeda License Agreement | License and Co-Funding Agreement | Subsequent Event      
Subsequent Event [Line Items]      
Agreement date   Oct. 07, 2020  
Ratio of Profit Sharing Structure for United States Commercialization   50/50 profit sharing  
Cash received as due under collaboration agreement   $ 300,000,000.0  
Development regulatory and sales milestones payments   $ 740,000,000.0  
Takeda License Agreement | Minimum | License and Co-Funding Agreement | Subsequent Event      
Subsequent Event [Line Items]      
Percentage of eligible to receive tiered royalties on net sales   20.00%  
Takeda License Agreement | Maximum | License and Co-Funding Agreement | Subsequent Event      
Subsequent Event [Line Items]      
Percentage of eligible to receive tiered royalties on net sales   25.00%  
Development regulatory and sales milestones payments   $ 740,000,000.0