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Stockholders' Equity - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended
Oct. 31, 2018
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2017
Class Of Stock [Line Items]        
Capital stock authorized for issuance   150,000,000    
Common stock, shares authorized   145,000,000 145,000,000  
Common stock, par value   $ 0.001 $ 0.001  
Preferred stock, shares authorized   5,000,000    
Preferred stock, par value   $ 0.001    
Common stock, shares outstanding   95,506,271 88,505,302  
Proceeds from the issuance of common stock   $ 60,521,739 $ 56,585,035 $ 12,419,119
Stock issued, price per share   $ 23.00 $ 5.25  
Common Stock Purchase Agreement | Janssen and JJDC        
Class Of Stock [Line Items]        
Shares issued 3,260,869      
Proceeds from the issuance of common stock $ 75,000,000      
Stock issued, price per share $ 23.00      
2004 Equity Incentive Plan, 2013 Equity Incentive Plan, and Inducement Grants        
Class Of Stock [Line Items]        
Common Stock, Share reserve for issuance   7,177,796