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Consolidated Statement of Stockholders' Equity - USD ($)
Total
Common stock issued for cash at $5.90 per share
Novartis
Amgen
Preferred Stock
Common Stock
Common Stock
Common stock issued for cash at $5.90 per share
Common Stock
Novartis
Common Stock
Amgen
Additional Paid-In Capital
Additional Paid-In Capital
Common stock issued for cash at $5.90 per share
Additional Paid-In Capital
Novartis
Additional Paid-In Capital
Amgen
Accumulated Other Comprehensive Income (loss)
Accumulated Deficit
Non-controlling Interest
Beginning Balance, Amount at Sep. 30, 2014 $ 165,985,255       $ 18 $ 147,026       $ 391,164,558         $ (224,771,159) $ (555,188)
Beginning Balance, Shares at Sep. 30, 2014         18,300 54,656,936                    
Exercise of warrants, Amount 401,876         $ 81       401,795            
Exercise of warrants, Shares           79,828                    
Exercise of stock options, Amount 101,870         $ 29       101,841            
Exercise of stock options, Shares           28,758                    
Stock-based compensation 10,232,897                 10,232,897            
Exercise of exchange rights, Amount 3,072         $ 5       3,067            
Exercise of exchange rights, Shares           5,250                    
Preferred stock converted to common stock, Amount         $ (2) $ 1,316       (1,314)            
Preferred stock converted to common stock, Shares         (2,648) 1,316,215                    
Common stock- Restricted Stock Units vesting, Amount (26,029)         $ 136       (26,165)            
Common stock- Restricted Stock Units vesting, Shares           136,307                    
Stock issuances     $ 25,000,000         $ 3,321       $ 24,996,679        
Stock issuances, Shares               3,321,383                
Foreign currency translation adjustments (136,425)                         $ (136,425)    
Net loss (91,940,882)                           (91,940,882)  
Ending Balance, Amount at Sep. 30, 2015 109,621,634       $ 16 $ 151,914       426,873,358       (136,425) (316,712,041) (555,188)
Ending Balance, Shares at Sep. 30, 2015         15,652 59,544,677                    
Exercise of warrants, Amount 3,691,398         $ 853       3,690,545            
Exercise of warrants, Shares           852,532                    
Exercise of stock options, Amount 133,869         $ 37       133,832            
Exercise of stock options, Shares           37,187                    
Stock-based compensation 11,595,816                 11,595,816            
Common stock- Restricted Stock Units vesting, Amount (670,765)         $ 428       (671,193)            
Common stock- Restricted Stock Units vesting, Shares           428,187                    
Stock issuances   $ 43,231,435   $ 9,000,000     $ 7,627   $ 1,257   $ 43,223,808   $ 8,998,743      
Stock issuances, Shares             7,627,119   1,256,983              
Foreign currency translation adjustments 143,874                         143,874    
Net loss (81,723,002)                           (81,723,002)  
Ending Balance, Amount at Sep. 30, 2016 95,024,259       $ 16 $ 162,116       493,844,909       7,449 (398,435,043) (555,188)
Ending Balance, Shares at Sep. 30, 2016         15,652 69,746,685                    
Exercise of stock options, Amount $ 271,931         $ 136       271,795            
Exercise of stock options, Shares 135,730         135,730                    
Stock-based compensation $ 7,891,595                 7,891,595            
Exercise of exchange rights, Amount 17,150         $ 5       17,145            
Exercise of exchange rights, Shares           5,000                    
Preferred stock converted to common stock, Amount         $ (16) $ 2,671       (2,655)            
Preferred stock converted to common stock, Shares         (15,652) 2,670,989                    
Common stock- Restricted Stock Units vesting, Amount (403,261)         $ 481       (403,742)            
Common stock- Restricted Stock Units vesting, Shares           481,212                    
Stock issuances       $ 12,420,000         $ 1,746       $ 12,418,254      
Stock issuances, Shares                 1,745,810              
Foreign currency translation adjustments 25,783                         25,783    
Net loss (34,380,295)                           (34,380,295)  
Ending Balance, Amount at Sep. 30, 2017 $ 80,867,162         $ 167,155       $ 514,037,301       $ 33,232 $ (432,815,338) $ (555,188)
Ending Balance, Shares at Sep. 30, 2017           74,785,426