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Consolidated Statement of Stockholders' Equity - USD ($)
Total
Common stock issued for cash at $5.86
Common stock issued for cash at $18.95
Preferred stock issued for cash at $1,000 per share
Common Stock Issued to Galloway
Common stock issued for cash at $5.90 per share
Novartis
Amgen
Preferred Stock
Preferred Stock
Preferred stock issued for cash at $1,000 per share
Common Stock
Common Stock
Common stock issued for cash at $5.86
Common Stock
Common stock issued for cash at $18.95
Common Stock
Common Stock Issued to Galloway
Common Stock
Common stock issued for cash at $5.90 per share
Common Stock
Novartis
Common Stock
Amgen
Additional Paid In Capital
Additional Paid In Capital
Common stock issued for cash at $5.86
Additional Paid In Capital
Common stock issued for cash at $18.95
Additional Paid In Capital
Preferred stock issued for cash at $1,000 per share
Additional Paid In Capital
Common Stock Issued to Galloway
Additional Paid In Capital
Common stock issued for cash at $5.90 per share
Additional Paid In Capital
Novartis
Additional Paid In Capital
Amgen
Accumulated Other Comprehensive Income (loss)
Accumulated Deficit
Noncontrolling Interest
Beginning Balance, Amount at Sep. 30, 2013 $ 25,734,789               $ 10   $ 124,859             $ 193,514,766                 $ (166,140,969) $ (1,763,877)
Beginning Balance, Shares at Sep. 30, 2013                 9,900   32,489,444                                  
Exercise of warrants, Amount 10,148,044                   $ 2,911             10,145,133                    
Exercise of warrants, Shares                     2,911,919                                  
Exercise of stock options, Amount 2,730,000                   $ 455             2,729,545                    
Exercise of stock options, Shares                     454,863                                  
Stock-based compensation 5,696,173                                 5,696,173                    
Stock issuances   $ 14,060,112 $ 112,581,559 $ 46,000,000 $ 500,000         $ 46   $ 3,072 $ 6,325 $ 132         $ 14,057,040 $ 112,575,234 $ 45,999,954 $ 499,868            
Stock issuances, Shares                   46,000   3,071,672 6,325,000 131,579                            
Settlements related to derivative liability 5,956,079                                 5,956,079                    
Preferred stock converted to common stock, Amount                 $ (38)   $ 9,272             (9,234)                    
Preferred stock converted to common stock, Shares                 (37,600)   9,272,459                                  
Deconsolidation of Calando Pharmaceuticals, Inc. 1,303,911                                                     1,303,911
Net loss (58,725,412)                                                   (58,630,190) (95,222)
Ending Balance, Amount at Sep. 30, 2014 165,985,255               $ 18   $ 147,026             391,164,558                 (224,771,159) (555,188)
Ending Balance, Shares at Sep. 30, 2014                 18,300   54,656,936                                  
Exercise of warrants, Amount 401,876                   $ 81             401,795                    
Exercise of warrants, Shares                     79,828                                  
Exercise of stock options, Amount 101,870                   $ 29             101,841                    
Exercise of stock options, Shares                     28,758                                  
Stock-based compensation 10,232,897                                 10,232,897                    
Exercise of exchange rights, Amount 3,072                   $ 5             3,067                    
Exercise of exchange rights, Shares                     5,250                                  
Preferred stock converted to common stock, Amount                 $ (2)   $ 1,316             (1,314)                    
Preferred stock converted to common stock, Shares                 (2,648)   1,316,215                                  
Common stock- Restricted Stock Units vesting, Amount (26,029)                   $ 136             (26,165)                    
Common stock- Restricted Stock Units vesting, Shares                     136,307                                  
Stock issuances             $ 25,000,000                 $ 3,321               $ 24,996,679        
Stock issuances, Shares                               3,321,383                        
Foreign Currency Translation Adjustments (136,425)                                                 $ (136,425)    
Net loss (91,940,882)                                                   (91,940,882)  
Ending Balance, Amount at Sep. 30, 2015 109,621,634               $ 16   $ 151,914             426,873,358               (136,425) (316,712,041) (555,188)
Ending Balance, Shares at Sep. 30, 2015                 15,652   59,544,677                                  
Exercise of warrants, Amount 3,691,398                   $ 853             3,690,545                    
Exercise of warrants, Shares                     852,532                                  
Exercise of stock options, Amount $ 133,869                   $ 37             133,832                    
Exercise of stock options, Shares 37,187                   37,187                                  
Stock-based compensation $ 11,595,816                                 11,595,816                    
Stock issuances           $ 43,231,435   $ 9,000,000             $ 7,627   $ 1,257           $ 43,223,808   $ 8,998,743      
Stock issuances, Shares                             7,627,119   1,256,983                      
Common stock- Restricted Stock Units vesting, Amount (670,765)                   $ 428             (671,193)                    
Common stock- Restricted Stock Units vesting, Shares                     428,187                                  
Foreign Currency Translation Adjustments 143,874                                                 143,874    
Net loss (81,723,002)                                                   (81,723,002)  
Ending Balance, Amount at Sep. 30, 2016 $ 95,024,259               $ 16   $ 162,116             $ 493,844,909               $ 7,449 $ (398,435,043) $ (555,188)
Ending Balance, Shares at Sep. 30, 2016                 15,652   69,746,685