0000879407 2026-01-08 2026-01-08 0000879407 1 2026-01-08 2026-01-08 0000879407 2 2026-01-08 2026-01-08 iso4217:USD pure shares S-3 424B5 EX-FILING FEES 333-292061 0000879407 ARROWHEAD PHARMACEUTICALS, INC. N/A N/A false S-3 ARROWHEAD PHARMACEUTICALS, INC. false Equity Common Stock, $0.001 par value per share true 3565892 64.50 230000034.00 0.0001381 31763.00 false Equity Pre-funded warrants to purchase common stock true 1550387 64.499 0.0001381 230000034.00 31763.00 0.00 0.00 31763.00 Assumes exercise in full of the underwriters' option to purchase up to 465,116 additional shares of common stock and includes 1,550,387 shares of common stock issuable upon the exercise of the pre-funded warrants to purchase common stock. Represents the sum of the offering price of the pre-funded warrants of $64.499 per pre-funded warrant and the exercise price of $0.001 per share issuable pursuant to the pre-funded warrants. The registration fee is calculated in accordance with Rule 457(r) of the Securities Act and represents deferred payment of the registration fees in connection with the Registrant's registration statement on Form S-3ASR (Registration No. 333-292061) paid with the filing of this prospectus supplement. Pursuant to Rule 416 under the Securities Act, the pre-funded warrants to purchase common stock being registered hereunder include such indeterminate number of additional shares of common stock as may be issued after the date hereof as a result of share splits, share dividends or similar transactions. The registration fee for the pre-funded warrants is being allocated to the shares of common stock issuable upon exercise of the pre-funded warrants.