Subsequent Events (Details) $ in Millions						1 Months Ended
	Nov. 20, 2025 USD ($)	Oct. 17, 2025 USD ($) program	Aug. 13, 2025 USD ($)	Feb. 24, 2025 USD ($)	Feb. 14, 2025 USD ($)	Aug. 31, 2025 USD ($)	Nov. 25, 2024 USD ($) program
Sarepta | Sarepta Collaboration Agreement
Subsequent Event [Line Items]
Upfront payment			$ 50.0	$ 500.0	$ 500.0	$ 50.0
Number of collaboration programs | program							13
Development milestone payments						$ 100.0
Sarepta | Sarepta Collaboration Agreement | Minimum
Subsequent Event [Line Items]
Sales-related milestone payments							$ 500.0
Sarepta | Sarepta Collaboration Agreement | Maximum
Subsequent Event [Line Items]
Sales-related milestone payments							$ 700.0
Subsequent Event | Novartis | Novartis Collaboration Agreement
Subsequent Event [Line Items]
Upfront payment		$ 200.0
Payment receivable upon target nomination		$ 30.0
Number of collaboration programs | program		4
Subsequent Event | Novartis | Novartis Collaboration Agreement | Minimum
Subsequent Event [Line Items]
Development milestone payments		$ 175.0
Sales-related milestone payments		285.0
Subsequent Event | Novartis | Novartis Collaboration Agreement | Maximum
Subsequent Event [Line Items]
Development milestone payments		245.0
Sales-related milestone payments		$ 370.0
Subsequent Event | Sarepta | Sarepta Collaboration Agreement
Subsequent Event [Line Items]
Development milestone payments	$ 200.0