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Stock Compensation - Narrative (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Stock compensation      
Stock compensation expense $ 266.1 $ 215.9 $ 188.4
Dividend yield (as percent) 0.00%    
Escient      
Stock compensation      
Asset acquisition, compensation expense $ 31.5    
Options      
Stock compensation      
Assumed annualized forfeiture rate 5.00%    
Unrecognized compensation cost for nonvested option $ 19.2    
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years) 1 year 1 month 6 days    
Restricted Stock Units (RSUs)      
Stock compensation      
Assumed annualized forfeiture rate 5.00%    
Unrecognized compensation cost for nonvested option $ 235.9    
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years) 1 year 7 months 6 days    
Performance Shares      
Stock compensation      
Stock compensation expense $ 30.1 17.2 7.8
Assumed annualized forfeiture rate 5.00%    
Unrecognized compensation cost for nonvested option $ 27.3    
Vesting period of recognition of the unrecognized compensation cost of nonvested awards (in years) 1 year 7 months 6 days    
Research and Development Expense      
Stock compensation      
Stock compensation expense $ 161.3 126.7 112.5
Selling, General and Administrative Expenses      
Stock compensation      
Stock compensation expense 102.5 86.1 73.2
Cost of Sales      
Stock compensation      
Stock compensation expense $ 2.3 $ 3.1 $ 2.7