License Agreements - Agenus (Details) - Agenus - USD ($) $ in Millions	1 Months Ended	12 Months Ended			120 Months Ended
	Feb. 28, 2017	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2024
License agreements
Royalty payments on future global net sales (as percent)	15.00%
License agreement, termination period (in months)	12 months
Milestone payment made under license agreement					$ 30.0
Shares divested (in shares)		600,000
Proceeds from sale of equity securities, FV-NI		$ 1.9
Investment owned (in shares)		0			0
Equity securities, FV-NI			$ 10.0
Realized and unrealized loss on equity investments		$ 8.2	$ 18.9	$ 9.9
Development, Regulatory and Commercialization Milestones
License agreements
Additional milestone payments under the license agreement		$ 500.0			$ 500.0
Development, Regulatory and Commercialization Milestones | Minimum
License agreements
Royalty payments on future global net sales (as percent)	6.00%
Development, Regulatory and Commercialization Milestones | Maximum
License agreements
Royalty payments on future global net sales (as percent)	12.00%