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License Agreements - MorphoSys (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Jan. 31, 2020
Long term investments $ 149,784   $ 149,784   $ 221,266  
Research and development expense 347,196 $ 343,511 700,569 $ 650,407    
Unrealized gain (loss) on long term investments (24,897) 26,765 (71,482) (944)    
Collaboration loss sharing $ 2,544 9,843 $ 7,286 20,327    
MorphoSys AG            
Ownership percentage (as a percent) 3.00%   3.00%      
Fair market value of our long term investments $ 17,500   $ 17,500   34,200  
Unrealized gain (loss) on long term investments (7,100) (9,200) (16,700) (32,900)    
MorphoSys AG            
Research and development expense $ 27,500 $ 19,400 $ 48,500 $ 34,300    
Associated future global development costs from the initiation of a Phase IIb trial, if elected to co-develop (as a percentage) 55.00% 55.00% 55.00% 55.00%    
Accrued and other liabilities $ 42,500   $ 42,500   $ 21,500  
MorphoSys AG | U.S.            
Profit (loss) sharing ratio 50.00% 50.00% 50.00% 50.00%    
Collaboration loss sharing $ 2,500 $ 9,800 $ 7,300 $ 20,300    
MorphoSys AG | Development and Regulatory Milestones | Maximum            
Additional milestone payments under the license agreement           $ 740,000
MorphoSys AG | Commercialization Milestones | Maximum            
Additional milestone payments under the license agreement           $ 315,000
MorphoSys AG | MorphoSys AG            
Funding of future development costs (as a percent)     45.00%      
MorphoSys AG | Incyte            
Funding of future development costs (as a percent)     55.00%