XML 56 R45.htm IDEA: XBRL DOCUMENT v3.22.2
License Agreements - Syros (Details)
$ / shares in Units, $ in Thousands, shares in Millions
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jan. 31, 2018
USD ($)
item
$ / shares
shares
Jun. 30, 2022
USD ($)
Jun. 30, 2021
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2021
USD ($)
Dec. 31, 2018
USD ($)
$ / shares
shares
Dec. 31, 2021
USD ($)
License agreements              
Long term investments   $ 149,784   $ 149,784     $ 221,266
Research and development expense   347,196 $ 343,511 700,569 $ 650,407    
Unrealized gain (loss) on long term investments   (24,897) 26,765 (71,482) (944)    
Syros Pharmaceuticals, Inc.              
License agreements              
Long term investments   $ 900   $ 900     $ 3,100
Ownership percentage (as a percent)   2.00%   2.00%      
Unrealized gain (loss) on long term investments   $ (200) $ (1,900) $ (2,200) $ (5,100)    
Syros Pharmaceuticals, Inc.              
License agreements              
Number of program targets | item 7            
Syros Pharmaceuticals, Inc. | Maximum              
License agreements              
Target selection and option exercise fee payment $ 54,000            
Syros Pharmaceuticals, Inc. | Development and Regulatory Milestones | Maximum              
License agreements              
Additional milestone payments under the license agreement 50,000            
Syros Pharmaceuticals, Inc. | Commercialization Milestones | Maximum              
License agreements              
Additional milestone payments under the license agreement $ 65,000            
Stock purchase agreement | Syros Pharmaceuticals, Inc.              
License agreements              
Purchase of common stock under Stock Purchase Agreement (in shares ) | shares 0.8            
Purchase price of common stock $ 10,000            
Per share price | $ / shares $ 12.61            
Amended stock purchase agreement | Syros Pharmaceuticals, Inc.              
License agreements              
Purchase of common stock under Stock Purchase Agreement (in shares ) | shares           0.1  
Purchase price of common stock           $ 1,400  
Per share price | $ / shares           $ 9.55