License Agreements - Innovent (Details) - Innovent $ in Millions	1 Months Ended		3 Months Ended
	Mar. 31, 2022 USD ($)	Dec. 31, 2018 USD ($)	Mar. 31, 2022 item
License agreements
Product candidates | item			3
Development and Regulatory Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement		$ 94.0
Regulatory Milestones | PEMAZYRE
License agreements
Amount recognized and received for the achievement of a predefined milestone	$ 5.0
Commercialization Milestones | Maximum
License agreements
Upfront and immediate milestone payment to be received under license agreement		$ 202.5