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Inventory (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Inventory    
Raw materials $ 14,717 $ 1,275
Work-in-process 37,267 39,895
Finished goods 18,857 15,768
Total inventories 70,841 56,938
Inventories - current 35,457 27,904 [1]
Inventories-noncurrent 35,384 $ 29,034 [1]
Inventory incurred prior to FDA approval $ 69,900  
Period of lower average per unit cost of materials 31 months  
[1] The condensed consolidated balance sheet at December 31, 2021 has been derived from the audited consolidated financial statements at that date.