CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021	[1]
Current assets:
Cash and cash equivalents	$ 2,256,759	$ 2,057,440
Marketable securities-available-for-sale (amortized cost $291,613 and $291,871 as of March 31, 2022 and December 31, 2021, respectively; allowance for credit losses $0 as of March 31, 2022 and December 31, 2021)	287,401	290,752
Accounts receivable	562,344	616,300
Inventory	35,457	27,904
Prepaid expenses and other current assets	146,130	126,278
Total current assets	3,288,091	3,118,674
Restricted cash and investments	1,700	1,720
Long term investments	174,681	221,266
Inventory	35,384	29,034
Property and equipment, net	729,217	723,920
Finance lease right-of-use assets, net	27,392	27,548
Other intangible assets, net	145,371	150,755
Goodwill	155,593	155,593
Deferred income tax asset	465,369	467,538
Other assets, net	31,423	37,304
Total assets	5,054,221	4,933,352
Current liabilities:
Accounts payable	152,547	172,110
Accrued compensation	83,657	108,962
Accrued and other current liabilities	609,290	533,595
Finance lease liabilities	2,796	2,635
Acquisition-related contingent consideration	37,873	37,006
Total current liabilities	886,163	854,308
Acquisition-related contingent consideration	204,127	206,994
Finance lease liabilities	31,385	31,632
Other liabilities	69,474	70,414
Total liabilities	1,191,149	1,163,348
Commitments and contingencies (Note 14)
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000,000 shares authorized; none issued or outstanding
Common stock, $0.001 par value; 400,000,000 shares authorized; 221,409,550 and 221,084,433 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively	221	221
Additional paid-in capital	4,625,780	4,567,111
Accumulated other comprehensive loss	(23,047)	(19,454)
Accumulated deficit	(739,882)	(777,874)
Total stockholders' equity	3,863,072	3,770,004
Total liabilities and stockholders' equity	$ 5,054,221	$ 4,933,352

[1] The condensed consolidated balance sheet at December 31, 2021 has been derived from the audited consolidated financial statements at that date.