Revenues (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Revenues
Total revenues	$ 2,986,267	$ 2,666,702	$ 2,158,759
Product revenues, net
Revenues
Total revenues	2,322,012	2,068,736	1,774,922
JAKAFI
Revenues
Total revenues	2,134,508	1,937,850	1,684,968
ICLUSIG
Revenues
Total revenues	4,668
PEMAZYRE
Revenues
Total revenues	109,395	105,002	89,954
MINJUVI
Revenues
Total revenues	68,531	25,884
OPZELURA
Revenues
Total revenues	4,910
Product royalty revenues
Revenues
Total revenues	569,255	392,966	306,337
JAKAVI Royalty Revenues
Revenues
Total revenues	337,991	277,902	225,913
OLUMIANT Royalty Revenues
Revenues
Total revenues	220,875	110,920	80,424
TABRECTA Royalty Revenues
Revenues
Total revenues	10,389	4,144
Milestone and contract revenues
Revenues
Total revenues	$ 95,000	$ 205,000	$ 77,500