CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 2,057,440	$ 1,513,008
Marketable securities-available-for-sale (amortized cost $291,871 and $288,199 as of December 31, 2021 and 2020, respectively; allowance for credit losses $0 as of December 31, 2021 and 2020)	290,752	288,369
Accounts receivable	616,300	481,994
Inventory	27,904	16,425
Prepaid expenses and other current assets	126,278	60,098
Total current assets	3,118,674	2,359,894
Restricted cash and investments	1,720	1,757
Long term investments	221,266	222,301
Inventory	29,034	19,548
Property and equipment, net	723,920	559,625
Finance lease right-of-use assets, net	27,548	28,451
Other intangible assets, net	150,755	172,291
Goodwill	155,593	155,593
Deferred income tax asset	467,538	2,054
Other assets, net	37,304	39,404
Total assets	4,933,352	3,560,918
Current liabilities:
Accounts payable	172,110	98,767
Accrued compensation	108,962	113,340
Accrued and other current liabilities	533,595	378,404
Finance lease liabilities	2,635	2,284
Acquisition-related contingent consideration	37,006	38,400
Total current liabilities	854,308	631,195
Acquisition-related contingent consideration	206,994	227,600
Finance lease liabilities	31,632	32,573
Other liabilities	70,414	58,282
Total liabilities	1,163,348	949,650
Commitments and contingencies (Note 15)
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000,000 shares authorized; none issued or outstanding as of December 31, 2021 and 2020
Common stock, $0.001 par value; 400,000,000 shares authorized; 221,084,433 and 219,489,329 shares issued and outstanding as of December 31, 2021 and 2020, respectively	221	219
Additional paid-in capital	4,567,111	4,352,864
Accumulated other comprehensive loss	(19,454)	(15,360)
Accumulated deficit	(777,874)	(1,726,455)
Total stockholders' equity	3,770,004	2,611,268
Total liabilities and stockholders' equity	$ 4,933,352	$ 3,560,918