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Fair value of financial instruments - Fair value on a recurring basis (Details)
$ in Thousands
6 Months Ended 12 Months Ended
Jun. 01, 2016
Jun. 30, 2020
USD ($)
Dec. 31, 2019
USD ($)
Fair value of financial instruments      
Long term investments (Note 9)   $ 248,731 $ 133,657
ARIAD | Contingent Consideration      
Roll forward of Level 3 liabilities      
Projected cash flows period 18 years    
ARIAD | Discount rate | Contingent Consideration      
Roll forward of Level 3 liabilities      
Valuation input (as a percent) 10    
ARIAD | Average Cost of Capital | Contingent Consideration      
Roll forward of Level 3 liabilities      
Valuation input (as a percent)   10  
ARIAD | Accrued and other current liabilities      
Roll forward of Level 3 liabilities      
Contingent consideration earned during the period but not yet paid   $ (7,100) (23,000)
Level 3 | Fair Value      
Roll forward of Level 3 liabilities      
Balance at the beginning of the period   277,000  
Contingent consideration earned during the period but not yet paid   (7,054)  
Payments made during the period   (8,627)  
Change in fair value of contingent consideration   12,681  
Balance at the end of the period   274,000 277,000
Recurring | Fair Value      
Fair value of financial instruments      
Cash and cash equivalents   1,326,730 1,832,684
Debt securities (government)   262,756 284,870
Long term investments (Note 9)   248,731 133,657
Total assets   1,838,217 2,251,211
Acquisition-related contingent consideration   274,000 277,000
Total liabilities   274,000 277,000
Recurring | Level 1      
Fair value of financial instruments      
Cash and cash equivalents   1,326,730 1,832,684
Long term investments (Note 9)   248,731 133,657
Total assets   1,575,461 1,966,341
Recurring | Level 2      
Fair value of financial instruments      
Debt securities (government)   262,756 284,870
Total assets   262,756 284,870
Recurring | Level 3      
Fair value of financial instruments      
Acquisition-related contingent consideration   274,000 277,000
Total liabilities   $ 274,000 $ 277,000