Accrued and other current liabilities (Tables)

6 Months Ended

Jun. 30, 2019

Schedule of accrued and other current liabilities

Accrued and other current liabilities consisted of the following (in thousands):

	June 30,		December 31,
	2019		2018
Royalties	$	34,376	$	25,087
Clinical related costs		64,963		98,607
Sales allowances		60,890		44,770
Construction in progress		2,847		7,673
Financing lease liability		—		18,696
Other current liabilities		47,398		34,568
Total accrued and other current liabilities	$	210,474	$	229,401