Accrued and other current liabilities (Tables)

3 Months Ended

Mar. 31, 2019

Accrued and other current liabilities

Schedule of accrued and other current liabilities

Accrued and other current liabilities at March 31, 2019 and December 31, 2018 consisted of the following (in thousands):

	March 31,		December 31,
	2019		2018
Royalties	$	20,077	$	25,087
Clinical related costs		65,874		98,607
Sales allowances		69,359		44,770
Construction in progress		16,087		7,673
Financing lease liability		—		18,696
Other current liabilities		39,905		34,568
Total accrued and other current liabilities	$	211,302	$	229,401