Property and equipment, net (Tables)

3 Months Ended

Mar. 31, 2018

Property and equipment, net

Schedule of property and equipment, net

	March 31,		December 31,
	2018		2017
	(in thousands)
Office equipment	$	15,978	$	14,674
Laboratory equipment		54,434		48,807
Computer equipment		51,876		51,351
Land		5,350		5,350
Building and leasehold improvements		218,413		214,245
		346,051		334,427
Less accumulated depreciation and amortization		(81,441)		(74,664)
Property and equipment, net	$	264,610	$	259,763