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Interim Consolidated Financial Information (Unaudited) - Narrative (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Interim Consolidated Financial Information (Unaudited)                      
Revenues relating to product                 $ 1,200,312 $ 882,404 $ 601,015
Revenues relating to product royalty                 160,791 110,711 74,821
Revenues relating to collaborative research and license agreement                 175,000 112,512 $ 77,857
JAKAFI and ICLUSIG                      
Interim Consolidated Financial Information (Unaudited)                      
Revenues relating to product $ 321,800 $ 322,000 $ 291,700 $ 264,800 $ 250,400 $ 236,600 $ 212,100        
JAKAFI                      
Interim Consolidated Financial Information (Unaudited)                      
Revenues relating to product               $ 183,300 $ 1,100,000 $ 852,800  
JAKAVI | Non-U.S.                      
Interim Consolidated Financial Information (Unaudited)                      
Revenues relating to product royalty 52,300 44,500 34,800 29,200 33,200 29,600 26,000 21,900      
Novartis and Eli Lilly                      
Interim Consolidated Financial Information (Unaudited)                      
Revenues relating to collaborative research and license agreement $ 70,000 $ 15,000 $ 0 $ 90,000 $ 42,900 $ 3,200 $ 8,200 $ 58,200